BHF Project Grant Awarded to Samantha Pitt: Cellular zinc is at the heart of sarcoplasmic reticulum calcium leak in cardiac muscle

Dr Samantha Pitt has just been awarded a 3 year BHF project grant to investigate how zinc regulates diastolic calcium leak to drive cardiac dysfunction. This award will enable the talented Amy Dorward to continue her work in this area as a PDRA. The project will use a combination of electrophysiology, molecular biology and cutting-edge microscopy techniques (supervised by Dr Juan Varela, School of Biology) to understand the intrinsic relationship between cardiac cellular Zn2+ and Ca2+-dynamics in the failing heart.

We would like to thank the BHF for their continued support of our research.